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John Loughlin
John Loughlin, Past President of OARSI,
Newcastle University, UK
Professor John Loughlin is a molecular and cell biologist with a background in genetics.
In 2002 he was awarded a tenured lectureship at Oxford and in 2008 he moved to Newcastle University as Professor of Musculoskeletal Research.
Professor Loughlin’s laboratory focuses on the identification and characterization of
those genes that confer risk towards the development and progression of OA. Through the application of powerful genome-wide association scans involving tens of thousands of OA patients, his group has identified a large number of OA susceptibility genes. His group’s efforts are directed toward comprehensive functional analysis of the associated variants within these genes, and in others that are emerging from ongoing scans. Professor Loughlin has published peer reviewed papers in a number of leading journals including Nature Genetics,
PNAS, The Lancet, British Medical Journal, American Journal of Human Genetics, PLoS Genetics, Human Molecular Genetics, Journal of Biological Chemistry, Arthritis & Rheumatism, and Osteoarthritis and Cartilage.
John Loughlin,英国纽卡斯尔大学教授,遗传学和细胞生物学家,国际骨关节炎研究协会前任主席,主要研究:骨关节炎发生进展的遗传学和相关的生物标记物。通过应用涉及数万名OA患者的强大的全基因组关联扫描,他的团队已经确定了大量的OA易感基因。团队工作主要针对这些基因中相关变异的全面功能分析,以及正在进行的扫描中出现的其他变异,对OA易感基因位点的表观遗传效应和整个疾病过程的分析。目前,已在Nature Genetics,PNAS,The Lancet,British Medical Journal,American Journal of Human Genetics,PLoS Genetics等国际著名杂志发表学术论文。